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Daily Archives: June 8, 2022
A Shot to Save the World: The Inside Story of the Life-or-Death Race for a COVID-19 Vaccine
疫情已經三年了,也許需要作出少少的反省了。。。 2018年年末2019年年初,神奇國度武漢突然出現了驚人的病毒傳染病。官方當時的處理手法是封鎖消息:結果當然首先將武漢封城。但病毒廣散甚快,死亡風險(是甚麼年齡組別的?那類人那種情況下?。。。目前似乎未有官方數據:印象是年長者及身體較弱的)亦高。初期此傳染病被稱為“武漢肺炎”。但神奇國度拒絕此稱呼:認為對其有侮辱含意,而世衛後來稱之為Covid -19,新冠肺炎。 2018年年末2019年年初,神奇國度武漢突然出現了驚人的病毒傳染病。官方當時的處理手法是封鎖消息:結果當然首先將武漢封城。但病毒廣散甚快,死亡風險(是甚麼年齡組別的?那類人那種情況下?。。。目前似乎未有官方數據:印象是年長者及身體較弱的)亦高。初期此傳染病被稱為“武漢肺炎”。但神奇國度拒絕此稱呼:認為對其有侮辱含意,而世衛後來稱之為Covid -19,新冠肺炎。 當 2020 年 1 月中國武漢出現一種神秘的呼吸道疾病時,幾乎沒有人做好準備。政界人士、政府官員、商界領袖和公共衛生專業人士對百年來最具破壞性的大流行毫無準備、對於百年來最具破壞性的流行病束手無策,就連許多世界上最大的藥廠和疫苗製造商都反應遲緩,無法拯救絕望的世人。 新冠傳染速度很快遍及全球,死亡陰影亦籠罩全球。。。各國亦很快制造了疫苗。‘’A Shot to Save the World – The Inside Story of the Life-or-Death Race for a COVID-19 Vaccine-Portfolio‘’一書就是講述了西方何處何背景何人如何研發了這些疫苗的故事 書中故事尤如小說般精彩起伏的劇情,生物醫學史上最激勵人心的篇章。華爾街日報特約記者Gregory Zuckerman 溯源超過40年背景,訪問超過300位產官學研專家,以宛如小說的筆法,生動展現新冠疫苗5大廠牌的激烈商戰 當病毒劫持世界,此時挺身而出的,竟是一群看起來不可靠的科學家和商人!其中包括狀似滿口謊話的法國商人Stephane Bancel(Moderna執行長)。沒有研發病毒疫苗經驗的土耳其移民Uğur Şahin(中文名吳沙忻)(BioNTech SE創辦人)。一個古怪的中西部人痴迷於昆蟲細胞、使用可疑技術的波士頓科學家Dan Baruch(腺病毒專家)。一位被被同儕排擠的英國科學家Luigi Warren和匈牙利籍研究 員 Katalin Karikó(mRNA研究先鋒)。 … Continue reading
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James Weatherall and Interdisciplinarity
在 2008 年經濟危機之後,巴菲特 (Warren Buffett) 發出了一句著名的警告:“當心極客的公式(Beware of geeks bearing formulas)”(geeks極客: 不合時宜或社交無能的人。奇異或怪誕的行為組成表演者)但正如 James Weatherall(加州大學歐文分校的邏輯學和科學哲學教授) 所展示的,並非所有的”極客”都是生來平等的。雖然華爾街的許多數學家和軟件工程師在他們的抽象概念在實踐中變得醜陋時都失敗了,但一類特殊的物理學家在金融革命方面有著更深的歷史。 Weatherall 將我們從世紀末的巴黎帶到 Rat Pack 時代的拉斯維加斯,從戰時政府實驗室到太平洋沿岸的 Yippie 公社,展示了物理學家如何成功地將他們的科學應用於經濟學中一些最棘手的問題,從選項對泡沫定價。 “The Physics of Wall Street: A Brief History of Predicting the Unpredictable“中說明: 危機的部分原因是數學建模的失敗。但更重要的是,一些非常成熟的金融機構未能像物理學家一樣思考。模型——無論是科學還是金融——都有局限性;它們在某些條件下會分解。而在 2008 年,複雜的模型落入了不了解其目的且不在乎的人手中。這是對科學的災難性濫用。 然而,解決方案是不要放棄模型;這是為了讓他們變得更好。 Weatherall 揭示了金融新時代風口浪尖上的人和想法。我們看到一位地球物理學家使用專為地震設計的模型來預測大規模的股市崩盤。我們發現了一個物理學家經營的對沖基金,它在 1990 … Continue reading
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